RESUMO
BACKGROUND: To compare the severity of pulmonary embolism (PE) and the long-term complications between patients with and without COVID-19, and to investigate whether the tools for risk stratification of death are valid in this population. METHODS: We retrospectively included hospitalized patients with PE from 1 January 2016 to 31 December 2022. Comparisons for acute episode characteristics, risk stratification of the PE, outcomes, and long-term complications were made between COVID and non-COVID patients. RESULTS: We analyzed 116 (27.5%) COVID patients and 305 (72.4%) non-COVID patients. In patients with COVID-19, the traditional risk factors for PE were absent, and the incidence of deep vein thrombosis was lower. COVID patients showed significantly higher lymphocyte count, lactate dehydrogenase, lactic acid, and D-dimer levels. COVID patients had PE of smaller size (12.3% vs. 25.5% main pulmonary artery, 29.8% vs. 37.1% lobar, 44.7% vs. 29.5% segmental and 13.2% vs. 7.9% subsegmental, respectively; p < 0.001), less right ventricular dysfunction (7.7% vs. 17.7%; p = 0.007) and higher sPESI score (1.66 vs. 1.11; p < 0.001). The need for mechanical ventilation was significantly higher in COVID patients (8.6% vs. 1.3%; p < 0.001); However, the in-hospital death was less (5.2% vs. 10.8%; p = 0.074). The incidence of long-term complications was lower in COVID cohort (p < 0.001). PE severity assessed by high sPESI and intermediate and high-risk categories were independently associated with in-hospital mortality in COVID patients. CONCLUSION: The risk of in-hospital mortality and the incidence of long-term complications were lower in COVID-19. The usual tools for risk stratification of PE are valid in COVID patients.
Assuntos
COVID-19 , Embolia Pulmonar , Humanos , Mortalidade Hospitalar , COVID-19/complicações , Estudos Retrospectivos , Embolia Pulmonar/complicações , Artéria Pulmonar , Medição de RiscoAssuntos
COVID-19/complicações , Mergulho , Máscaras , Síndrome do Desconforto Respiratório/terapia , Insuficiência Respiratória/terapia , Dispositivos de Proteção Respiratória , Adolescente , Adulto , Criança , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Oxigênio/administração & dosagem , Impressão Tridimensional , Síndrome do Desconforto Respiratório/etiologia , Insuficiência Respiratória/prevenção & controle , SARS-CoV-2 , Adulto JovemRESUMO
No disponible
Assuntos
Humanos , Feminino , Adulto , Trombose Venosa/sangue , Trombose Venosa/patologia , Flebite/sangue , Flebite/metabolismo , Terapêutica/métodos , Embolia Pulmonar/metabolismo , Embolia Pulmonar/patologia , Trombose Venosa/complicações , Trombose Venosa/metabolismo , Flebite/complicações , Flebite/diagnóstico , Terapêutica/normas , Embolia Pulmonar/complicações , Embolia Pulmonar/diagnósticoRESUMO
No disponible
No disponible
